Formulation and Pharmaceutical Quality Evaluation of Tablets Containing Extract of Cinnamomum burmannii BARK and Colocasia esculenta (L) Schott Leaves

نویسندگان

چکیده

Cinnamon bark (Cinnamomum burmannii) is used traditionally and has an ingredient containing cinnamic acid compounds. Colocasia esculenta (L) Schott leaves contains of flavonoids, alkaloids, tannins, saponins, steroids, terpenoids. Both the plants C. burmannii have potential as anti-diabetics because they can lower blood glucose levels. This study aims to make combination tablets extract with various concentrations PVP K30 binder. research made four formulas concentration K30, namely F1 (2%), F2 (3%), F3 (4%), F4 (5%). Tablet preparations were prepared by wet granulation method. analysis flavonoids quercetin markers. The results showed that flat, round in shape, light green, had a slightly bitter taste, distinctive aromatic odor. differences binder 2-5% could affect hardness, friability, disintegration time, tablet dissolution (p<0.05). tablet's hardness was 3.65-5.01 KP; friability 0.705%, time <15 minutes, 84.61% 40 minutes. levels flavonoid 4.21% 8.03% acid. A 5% (F4) best quality.

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ژورنال

عنوان ژورنال: Jurnal Mandala Pharmacom Indonesia

سال: 2023

ISSN: ['2598-9979', '2442-6032']

DOI: https://doi.org/10.35311/jmpi.v9i1.292